Guthrie's squad car found on a water covered road around 3PM Monday.
"Our aircraft is up, searching from the air," Sgt. Sheldon Lyon said. "We have numerous boats out - not only the water patrol from the highway patrol, but the Missouri Conservation Department and Sheriff's Departments from the area are assisting."
Just what happened to Guthrie is unclear. Lyon confirmed that Trooper Guthrie has drown, and said there is no reason to suspect foul play in the trooper's disappearance.
Lyon said it is possible, Guthrie got out of his car and was swept away by water rushing across the road.
"It's very deceiving," Lyon said. "You look at these fields around us. they're very flat. When the Missouri River gets outside of its banks, if you look at the water you think it looks like a lake. When you examine what it's doing, there is current and in some locations that current is very strong."
Trooper Josh White was one of the first to search for Trooper Guthrie.
White said it's a little harder searching for a colleague and a friend.
"We just had one thing in mind and that's trying to find him," he said. "Being somebody that you work with closely and know well then the urgency kind of hits home."
"Our hearts and prayers go out to his family so they could have some peace and the things can turn out better," he said.
Twenty-four Missouri State Troopers are taking part in the recovery effort. Dozens of others, including fire fighters, paramedics, family and friends are also pitching in for the search for Trooper Guthrie. They hope to find his body soon to provide some closure to this event.
The search team believes they know the general area where Guthrie's body is but the current is too swift and too dangerous for divers.
A Blackhawk helicopter is bringing in 200 pound sandbags to dam up the area.
All of this further stresses how dangerous it can be to be near the river.